Author

C.-X. Li

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Bioengineering· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:differential expression· 4 Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 3 Organism:human· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Organism:chicken / avian· 1

Frequent Co-Authors

E. C. Holmes· 2 shared A. Bhagwat· 1 shared A. Cerutti· 1 shared A. Kesson· 1 shared A. Ranki· 1 shared A. Wheelock· 1 shared B. Huang· 1 shared B. Pei· 1 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersMicrobiology

E. C. Holmes

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

A Germinal Center Checkpoint of AIRE in B Cells Limits Antibody Diversification

J. Z. Zhou, B. Pei, G. Sun, M. Pawlitz, W. Zhang, x. Li, F. Yao, K. C. Hokynar, C.-X. Li, M. L. Perera, S. Wei, S. Zheng, L. A. Polin, J. M. Poulik, A. Ranki, , K. Chen

This study identifies AIRE as a checkpoint in germinal center B cells that limits antibody diversification by inhibiting AID function, leading to autoimmunity and impaired immune responses.

bioRxiv · Jan 10, 2024 · PreprintImmunology

Diagnosis and analysis of unexplained cases of childhood encephalitis in Australia using metagenomic next-generation sequencing

C.-X. Li, R. Burrell, R. C. Dale, A. Kesson, C. C. Blyth, J. E. Clark, N. Crawford, C. A. Jones, P. N. Britton, E. C. Holmes

This study uses metagenomic sequencing to identify viral and immune-mediated causes of unexplained childhood encephalitis in Australia, finding respiratory viruses in five cases and immune-mediated causes in six.

bioRxiv · May 10, 2021 · PreprintMicrobiology

Meta-transcriptomic discovery of a divergent circovirus and a chaphamaparvovirus in captive reptiles with proliferative respiratory syndrome

W.-S. Chang, C.-X. Li, J. Hall, J.-S. Eden, T. H. Hyndman, E. C. Holmes, K. Rose

The paper identifies two novel viruses in captive bearded dragons with respiratory disease using meta-transcriptomic sequencing.

bioRxiv · Aug 24, 2020Microbiology

Decreased miR-24-3p potentiates DNA damage responses and increases susceptibility to COPD

J. Nouws, F. Wan, E. Finnemore, W. Roque, S. Kim, I. Bazan, C.-x. Li, M. Skold, X. Yan, V. Neumeister, C. J. Britto, R. Bindra, A. Wheelock, J. Gomez-Villalobos, N. Kaminski, , M. Sauler

The paper identifies miR-24-3p as a regulator of DNA damage responses and COPD susceptibility, showing its suppression in COPD and its role in modulating apoptosis and DNA repair.

bioRxiv · May 22, 2020 · PreprintCell Biology

The permeabilized SecY protein-translocation channel can serve as a nonspecific sugar transporter

S. Mei, C. Xie, H. Mi, C. Xue, Q. Guo, G.-Q. Du, G.-B. Li, C.-X. Li, Y.-N. Qu, M.-H. Xiong, Y. Jiang, T.-W. Tan, S.-T. Yang, L.-H. Fan

This paper shows that modifying the SecY protein-translocation channel in bacteria allows it to transport various sugars, enabling rapid growth on multiple monosaccharides and bypassing typical transport limitations.

bioRxiv · Jul 27, 2018 · PreprintBioengineering