Cell BiologybioRxiv
MMD scaffolds ACSL4 and MBOAT7 to promote polyunsaturated phospholipid synthesis and susceptibility to ferroptosis
V. V. Phadnis, J. Snider, V. Wong…·R. A. Weinberg
This paper identifies MMD as a scaffold protein that promotes ferroptosis by facilitating the synthesis of arachidonoyl-phospholipids through interactions with ACSL4 and MBOAT7.
DOI 10.1016/j.celrep.2023.113023