Author

J. Snider

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Pharmacology & Toxicology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 3 Organism:human· 2 Assay:protein structure· 2 Organism:C. elegans· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

I. Stagljar· 4 shared A. R. Burns· 2 shared A. S. Vaidya· 2 shared B. Geng· 2 shared B. M. Palmeira· 2 shared E. M. Redman· 2 shared I. Zasada· 2 shared J. J. Dowling· 2 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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4 shared papersPharmacology & Toxicology

I. Stagljar

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Omicron Spike Protein Is Vulnerable to Reduction

I. Stagljar, Z. Yao, B. Geng, E. Marcon, S. Pu, H. Tang, J. Merluza, A. Bello, J. Snider, P. Lu, H. Wood

This study shows that Omicron SARS-CoV-2 spike proteins are more susceptible to reduction due to mutations in the receptor binding module, which affects their stability and binding activity.

bioRxiv · Jan 6, 2023Biochemistry

MMD scaffolds ACSL4 and MBOAT7 to promote polyunsaturated phospholipid synthesis and susceptibility to ferroptosis

V. V. Phadnis, J. Snider, V. Wong, K. D. Vaccaro, T. Kunchok, J. Allen, Z. Yao, B. Geng, K. Weiskopf, I. Stagljar, W. S. Henry, R. A. Weinberg

This paper identifies MMD as a scaffold protein that promotes ferroptosis by facilitating the synthesis of arachidonoyl-phospholipids through interactions with ACSL4 and MBOAT7.

bioRxiv · Sep 1, 2022Cell Biology

Nementin is a Nematode-Selective Small Molecule Agonist of Neurotransmitter Release

S. Harrington, J. J. Knox, A. R. Burns, K.-L. Choo, A. Au, M. Kitner, C. Haeberli, J. Pyche, C. D'Amata, Y.-H. Kim, J. Volpatti, M. Guiliani, J. Snider, V. Wong, B. M. Palmeira, , P. Roy

A C. elegans-based screening pipeline identifies a selective nematicide that also potentiates acetylcholinesterase inhibitors.

bioRxiv · Mar 12, 2022 · PreprintPharmacology & Toxicology

Selective Control of Parasitic Nematodes Using Bioactivated Nematicides

A. R. Burns, R. J. Ross, M. Kitner, J. Volpatti, A. S. Vaidya, E. Puumala, B. M. Palmeira, E. M. Redman, J. Snider, S. Marwah, S. W. Chung, M. H. MacDonald, J. Tiefenbach, C. Hu, Q. Xiao, , P. Roy

This study identifies selectivins, a family of imidazothiazole nematicides that are selectively activated in nematodes, offering effective and selective control of plant-parasitic nematodes.

bioRxiv · Mar 11, 2022 · PreprintPharmacology & Toxicology

New Structural Insights into the Function of the Catalytically Active Human Taspase1

N. Nagaratnam, S. Delker, R. Jernigan, T. E. Edwards, J. Snider, D. Thifault, D. Williams, B. L. Nannenga, M. Stofega, L. Sambucetti, J. Hsieh, A. J. Flint, P. Fromme, J. M. Martin-Garcia

This study determines the crystal structure of catalytically active human Taspase1 and identifies a long helical domain essential for its enzymatic activity, suggesting it as a potential target for anticancer therapeutics.

bioRxiv · Nov 26, 2020Biochemistry