BiophysicsbioRxiv
Active Transcription and Epigenetic Reactions Synergistically RegulateMeso-Scale Genomic Organization
A. Kant, Z. Guo, V. Vinayak…·V. Shenoy
This study introduces a mesoscale model to show how transcription and epigenetic reactions regulate heterochromatin domain sizes, finding that transcription loss increases domain size and compaction.