ImmunologybioRxiv
An integrated signaling threshold initiates IgG response towards virus-like immunogens
W. Wholey, A. R. Meyer, S.-T. Yoda…·W. Cheng
The paper identifies that a combination of surface antigen density and internal nucleic acids is sufficient to initiate strong antiviral IgG responses without T cell help or Toll-like receptor signaling.
DOI 10.4049/jimmunol.2400101