NeurosciencebioRxivPreprint
Disease stage-sensitive MFSD2A-caveolae axis insigates hippocampal blood-brain barrier disruption in Alzheimer's disease
Yiyi Zhu, Danjie Yang, jiayi chen…·Chenju Yi
The paper identifies MFSD2A loss in hippocampal endothelial cells as an early stage-specific factor contributing to BBB disruption in Alzheimer's disease and shows that restoring MFSD2A can mitigate pathology and cognitive deficits.