An atlas of inter- and intra-tumor heterogeneityof apoptosis competency in colorectal cancertissue at single cell resolution
A. U. Lindner, M. Salvucci, E. MCDonough, S. Cho, X. Stachtea, E. P. O'Connell, A. D. Corwin, A. Santamaria-Pang, S. Carberry, M. Fichtner, S. Van Schaeybroeck, P. Laurent-Puig, J. P. Burke, D. McNamara, M. Lawler, , J. H. Prehn
The paper generates an atlas of apoptosis susceptibility heterogeneity in colorectal cancer using single-cell analysis and ODE modeling, identifying intrinsic cellular differences in apoptosis competency.
bioRxiv · Mar 19, 2021Cancer Biology