S. Dasgupta

RAPID HEMATOCRIT ESTIMATION USING A FOLD-CREASE INDUCED FAST FLOWING PAPER SENSOR

This paper develops a fast-flowing paper sensor using fold-crease regions to estimate hematocrit efficiently with low cost and minimal sample volume.

DNA methylation database for gynecological cancer detection, classification and assay development

This study creates a DNA methylation database for gynecological cancers and develops qMSP assays for detection and classification.

Assessing mechanisms driving phenol isopropylated phosphate (IPP)- induced larval photomotor response deficits in zebrafish

This study investigates IPP-induced developmental toxicity in zebrafish embryos, finding morphological abnormalities and disrupted larval photomotor responses linked to DNA hypermethylation and gene expression changes in the brain and eye.

Molecular insights into the oligosaccharide binding, recognition and hydrolysis by a fungal exo-beta-(1,3)-glucanase

This study characterizes the structure and function of Aspergillus oryzae exo-β-(1,3)-glucanase, revealing substrate binding mechanisms and insights for industrial enzyme engineering.

A mouse model of TB-associated lung fibrosis reveals persistent inflammatory macrophage populations during treatment

This study uses a mouse model of TB infection to investigate fibrosis mechanisms, finding persistent inflammatory macrophages and elevated matrix remodeling enzymes during treatment.

A Postdoctoral Training Program in Bioimage Analysis

This paper describes a postdoctoral training program in bioimage analysis, highlighting its components, outcomes, and implications for training experts in professional skills.

Single cell sequencing of zebrafish kidney marrows reveals AHR2-dependent endogenous regulation of hematopoiesis

This study uses single-cell sequencing in zebrafish to show AHR2 regulates gene expression in immune cells without altering cell proportions.

Evolution of the substrate specificity of an RNA ligase ribozyme from phosphorimidazole- to triphosphate-activation

This study shows that an RNA ligase ribozyme evolved from using phosphorimidazole-activated substrates to triphosphate-activated substrates through neutral mutations, leading to a new structure and function.

Experimental type 1 diabetes metabolically rejuvenates CD8+ T cells for improved control of tumor growth through an IGF1-IGF1R axis

This study shows that experimental type 1 diabetes enhances CD8+ T cell function via the IGF1-IGF1R axis, leading to better tumor control.

Flame retardant tetrabromobisphenol A (TBBPA) disrupts histone acetylation during zebrafish maternal-to-zygotic transition

This study shows TBBPA exposure disrupts zebrafish early development by inhibiting histone acetylation during zygotic genome activation.

Addressing anemia severity in antimony-resistant Leishmania donovani infection at the nexus of oxidative outburst and iron transit

This study investigates how antimony-resistant Leishmania donovani strains manage iron and oxidative stress, leading to anemia, and identifies potential therapeutic targets.

Molecular crowding facilitates ribozyme-catalyzed RNA assembly

This study shows that molecular crowding supports ribozyme-catalyzed RNA assembly under low Mg2+ conditions, suggesting a role in early life.

RNA-catalyzed RNA Ligation within Prebiotically Plausible Model Protocells

This study demonstrates RNA-catalyzed RNA ligation within fatty acid vesicles by using a ribozyme functional at low Mg2+ concentrations and prebiotically relevant molecules to stabilize the system.

Role of vegetation characteristics on the distribution of three hornbill species in and around Pakke Tiger Reserve, Arunachal Pradesh, India

The study examines how vegetation characteristics influence the distribution of three hornbill species in and around Pakke Tiger Reserve, finding that tree density, fruiting trees, canopy cover, and diversity are key factors.

Global analysis of human-to-mouse contact-dependent intercellular mRNA and lncRNA transfer in cell culture

The paper quantifies mRNA and lncRNA transfer between human and mouse cells in co-culture, showing non-selective transfer and correlation with donor gene expression.

Design, Fabrication, and Theoretical Investigation of a Cost-Effective Laser Printing Based Colorimetric Paper Sensor for Non-Invasive Glucose and Ketone Detection

This paper presents a laser-printing based colorimetric paper sensor for non-invasive glucose and ketone detection in urine, validated by a dynamic model and a web/desktop app for accurate quantification.

Non-enzymatic assembly of active chimeric ribozymes from aminoacylated RNA oligonucleotides

This study shows aminoacylated RNAs can assemble into active chimeric ribozymes, suggesting aminoacylation may have aided ribozyme formation before ribosomes evolved.

Assessment of dependency and consumption pattern of different forest products by the forest fringe villages of Shivalik Himalaya, Uttarakhand, India

The paper assesses timber, fuelwood, and fodder consumption patterns in forest fringe villages of Uttarakhand, India, finding high local extraction and socio-economic determinants of dependency.

Role of Anthropogenic drivers in altering the forest community structure in a prime tiger habitat in central India

The paper examines how anthropogenic factors alter plant community structure in a tiger habitat, finding significant dissimilarity in species composition and increased regeneration with distance from human settlements.

Stratification Of Chemotherapy-Treated Stage III Colorectal Cancer Patients Using Multiplexed Imaging And Single Cell Analysis Of T Cell Populations

This study uses multiplexed imaging and single-cell analysis to classify immune cells in stage III colorectal cancer patients, finding that multi-marker Treg classification better predicts survival than single markers.

Physics of lumen growth

The paper models the dynamics of intercellular secretory lumen formation, predicting a critical pumping threshold and a transition between monotonous and oscillatory regimes during luminogenesis.