Spatial transcriptomics maps molecular and cellular requirements for CD4+ T cell-dependent immunity to malaria.
C. G. Williams, M. d. L. Moreira, T. Asatsuma, O. P. Skinner, H. J. Lee, S. Li, I. Barrera, E. Murray, M. S. F. Soon, J. A. Engel, D. S. Khoury, S. Asad, T. M. Steiner, R. Joseph, Y. Alexandre, , A. Haque
This paper uses spatial transcriptomics to map CD4+ T cell and B cell interactions in the spleen during malaria infection, revealing their localization and molecular requirements for immunity.
bioRxiv · Feb 23, 2023 · PreprintImmunology