Author

R. Joseph

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Ecology· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:gene regulatory network inference· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

S. A. Mani· 2 shared A. Haque· 1 shared A. P. Deshmukh· 1 shared B. Sen· 1 shared C. Fernandez Petty· 1 shared C. Fu· 1 shared C. G. Williams· 1 shared D. S. Khoury· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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2 shared papersCell Biology

S. A. Mani

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Spatial transcriptomics maps molecular and cellular requirements for CD4+ T cell-dependent immunity to malaria.

C. G. Williams, M. d. L. Moreira, T. Asatsuma, O. P. Skinner, H. J. Lee, S. Li, I. Barrera, E. Murray, M. S. F. Soon, J. A. Engel, D. S. Khoury, S. Asad, T. M. Steiner, R. Joseph, Y. Alexandre, , A. Haque

This paper uses spatial transcriptomics to map CD4+ T cell and B cell interactions in the spleen during malaria infection, revealing their localization and molecular requirements for immunity.

bioRxiv · Feb 23, 2023 · PreprintImmunology

Mucociliary Clearance Augmenting Drugs Block SARS-Cov-2 Replication in Human Airway Epithelial Cells

J. Campos-Gomez, C. Fernandez Petty, M. Mazur, L. Tang, G. M. Solomon, R. Joseph, Q. Li, J. E. Peabody Lever, S. S. Hussain, K. S. Harrod, E. Onuoha, H. Kim, S. M. Rowe

This study tests mucoactive drugs that enhance mucociliary clearance and finds three inhibit SARS-CoV-2 replication in human airway epithelial cells by improving ciliary function and redox state.

bioRxiv · Jan 30, 2023 · PreprintMicrobiology

Acquisition of cancer stem cell properties during EMT requires cell division

P. den Hollander, S. V. Vasaikar, M. Castaneda, R. Joseph, A. P. Deshmukh, T. Zhao, M. Pietila, C. Fu, W. F. Symmans, R. Soundararajan, S. A. Mani

This study shows that cancer cells acquire stem cell properties during EMT through cell division, not the mesenchymal program, and highlights the importance of EMT-induced stemness markers for clinical prediction.

bioRxiv · Jul 1, 2021 · PreprintCell Biology

Functional single-cell profiling identifies that exosomes are associated with increased immune cell infiltration in non-metastatic breast cancer

M. Fathi, R. Joseph, J. R. T. Adolacion, M. Martinez-Paniagua, X. An, K. Gabrusiewicz, S. A. Mani, N. Varadarajan

The paper develops a single-cell technique to profile exosome secretion in breast cancer cells and finds that non-metastatic cells secrete more exosomes, which correlates with better prognosis and immune infiltration.

bioRxiv · Dec 14, 2020Cancer Biology

Empirical Analyses of Associations between State Political Attitudes and Gains in Health Insurance Coverage after the Affordable Care Act (ACA)

R. Joseph, B. Sen

This study examines the relationship between state political attitudes and health insurance gains after the ACA, finding higher insurance gains in states with higher anti-Obama voting despite fewer Medicaid expansions.

bioRxiv · Apr 11, 2019 · PreprintEcology