Author

Y. Dashti

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:bacteria (other)· 2 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

E. Mahenthiralingam· 2 shared G. L. Challis· 2 shared G. Webster· 2 shared A. J. Mullins· 1 shared A. Mullins· 1 shared A. R. Tyler· 1 shared A. Vocat· 1 shared B. Bunk· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersMicrobiology

E. Mahenthiralingam

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Mircubactin B rescues the lethal effect of cell wall biosynthesis mutations in Bacillus subtilis.

B. Kepplinger, X. Wen, A. R. Tyler, B.-Y. Kim, J. Brown, P. Banks, Y. Dashti, E. S. Mackenzie, C. Wills, Y. Kawai, K. J. Waldron, N. E. E. Allenby, L. J. Wu, M. J. Hall, J. Errington

The paper identifies mirubactin B, a compound that rescues growth defects in Bacillus subtilis rod-complex mutants, showing activity beyond simple iron sequestration.

bioRxiv · Apr 24, 2022 · PreprintMicrobiology

Discovery and Biosynthesis of Persiathiacins: Unusual Polyglycosylated Thiopeptides Active against Multi-drug resistant Tuberculosis

Y. Dashti, F. Mohammadipanah, M. J. Belousoff, A. Vocat, D. Zabala, C. D. Fage, I. Romero-Canelon, B. Bunk, C. Sproer, J. Overmann, S. T. Cole, G. L. Challis

This study discovers two novel polyglycosylated thiopeptides, persiathiacins A and B, active against drug-resistant tuberculosis and identifies their biosynthetic gene cluster.

bioRxiv · Oct 24, 2021 · PreprintMicrobiology

Discovery and biosynthesis of gladiochelins: unusual lipodepsipeptide siderophores from Burkholderia gladioli

Y. Dashti, I. Nakou, A. Mullins, G. Webster, X. Jian, E. Mahenthiralingam, G. Challis

This study identifies two novel lipodepsipeptide siderophores in Burkholderia gladioli, showing they bind ferric iron and are involved in iron acquisition.

bioRxiv · Jun 16, 2020 · PreprintMicrobiology

Kill and cure: genomic phylogeny and bioactivity of a diverse collection of Burkholderia gladioli bacteria capable of pathogenic and beneficial lifestyles

C. Jones, G. Webster, A. J. Mullins, M. Jenner, M. J. Bull, Y. Dashti, T. Spilker, J. Parkhill, T. R. Connor, J. J. LiPuma, G. L. Challis, E. Mahenthiralingam

This study examines the genomic phylogeny and bioactivity of 206 Burkholderia gladioli strains, identifying toxin-producing clades and potential therapeutic strategies for CF-related infections.

bioRxiv · Apr 9, 2020Microbiology