Y. Gotoh

Effect of phage variation on Shiga toxin 2 (Stx2) production and the virulence of Stx-producing Escherichia coli

This study examines how variations in Stx2 phages affect Stx2 production and virulence in O145:H28 STEC strains, revealing differences in production levels based on phage type and repressor type.

PDZD8-FKBP8 tethering complex at ER-mitochondria contact sites regulates mitochondrial complexity

This study identifies FKBP8 as the tethering partner of PDZD8 at ER-mitochondria contact sites, showing their interdependence in regulating mitochondrial morphology.

Age-associated reduction of nuclear shape dynamics in excitatory neurons of the visual cortex

The paper examines age-related changes in nuclear shape dynamics in excitatory neurons of the visual cortex using time-lapse imaging and finds reduced morphological dynamics in aged nuclei.

Glutamine synthetase mRNA releases sRNA from its 3'UTR to regulate carbon/nitrogen metabolic balance

The paper shows that glutamine synthetase mRNA produces an sRNA, GlnZ, which regulates carbon/nitrogen metabolism by repressing SucA expression.

Year-round dynamics of amplicon sequence variant communities differ among eukaryotes, Mimiviridae, and prokaryotes in a coastal ecosystem

A one-year observation of coastal microbial communities revealed similar but different community dynamics for eukaryotes, a group of large viruses, and prokaryotes.

Prophages integrating into prophages: a mechanism to accumulate type III secretion effector genes and duplicate Shiga toxin-encoding prophages in Escherichia coli

The paper identifies a mechanism where prophages integrate into other prophages in Escherichia coli, leading to the duplication of Shiga toxin-encoding prophages and the accumulation of type III secretion effector genes.

NUDT21 links mitochondrial IPS-1 to RLR-containing stress granules and activates host antiviral defense

This study shows NUDT21 connects RLRs in stress granules to mitochondrial IPS-1, enabling antiviral defense by facilitating type I IFN induction.

Comprehensive in virio structure probing analysis of the influenza A virus identifies a functional RNA structure involved in replication and segment interactions

A universal subcuticular bacterial symbiont of a coral predator, the crown-of-thorns starfish, in the Indo-Pacific

This study identifies a universal bacterial symbiont, COTS27, found in the subcuticular space of crown-of-thorns starfish across the Indo-Pacific, suggesting an ancient symbiotic relationship.

Peroxisomes control mitochondrial dynamics and the mitochondrion-dependent pathway of apoptosis

This study shows peroxisomes regulate mitochondrial dynamics and apoptosis by affecting Drp1-mediated fission and caspase activation.