Author

Y. Hooks

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Assay:whole-genome sequencing· 2 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1

Frequent Co-Authors

P. J. Campbell· 3 shared A. Y. Warren· 2 shared D. Leongamornlert· 2 shared M. A. Sanders· 2 shared R. Rahbari· 2 shared S. Behjati· 2 shared T. J. Mitchell· 2 shared A. Cagan· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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3 shared papersCancer Biology

P. J. Campbell

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Author profile →

3 papers

Recent·Most cited

Multifocal, multiphenotypic tumours arising from an MTOR mutation acquired in early embryogenesis

C. N. Pacyna, M. Anandapadamanaban, K. W. Loudon, I. M. Hay, O. Perisic, R. Li, M. Byrne, L. Allen, K. Roberts, Y. Hooks, A. Y. Warren, G. D. Stewart, M. R. Clatworthy, S. Teichmann, S. Behjati, , T. J. Mitchell

The paper traces the origin of four synchronous renal tumours in a child to an early embryonic MTOR mutation, showing its role in tumour development and clinical implications.

bioRxiv · Dec 12, 2023Cancer Biology

Clonal diversification and histogenesis of malignant germ cell tumours

T. R. W. Oliver, L. Chappell, R. Sanghvi, L. Deighton, N. Ansari-Pour, S. Dentro, M. D. Young, T. H. H. Coorens, H. Jung, T. M. Butler, M. D. C. Neville, D. Leongamornlert, M. A. Sanders, Y. Hooks, A. Cagan, , S. Behjati

This study analyzes the genome and transcriptome of 547 GCT histological units to explore clonal diversification and histogenesis, finding unifying genomic and transcriptional features across GCTs.

bioRxiv · Feb 1, 2022Cancer Biology

The mutational landscape of normal human endometrial epithelium

L. Moore, D. Leongamornlert, T. H. Coorens, M. A. Sanders, P. Ellis, K. Dawson, F. Maura, J. Nangalia, P. S. Tarpey, S. F. Brunner, H. Lee-Six, R. Rahbari, S. Moody, Y. Hooks, K. Mahbubani, , M. R. Stratton

This study characterizes the mutational landscape of normal human endometrial epithelium, revealing age-related mutation burdens and driver mutations in cancer genes.

bioRxiv · Dec 24, 2018Cancer Biology