Engineered vasculature induces functional maturation of pluripotent stem cell-derived islet organoids
K. V. Nguyen Ngoc, S. Sai, Y. Jun, R. H. F. Bender, V. Kravets, H. Zhu, C. J. Hatch, M. Schlichting, R. Gaetani, M. Mallick, S. J. Hachey, K. Christman, S. C. George, C. C. Hughes, M. Sander
This study shows that engineered vasculature enhances the function of stem cell-derived islet organoids by improving calcium influx and insulin secretion in beta-cells.
bioRxiv · Oct 28, 2022 · PreprintCell Biology