Hyperglycosylation of prosaposin in tumor DCs promotes immune escape in cancer
P. Sharma, X. Zhang, K. Ly, J. H. Kim, Q. Wan, J. Kim, M. Lou, L. Kain, L. Teyton, F. Winau
This study shows that hyperglycosylation of prosaposin in tumor DCs leads to immune escape by impairing antigen presentation and T cell activation.
bioRxiv · Jun 14, 2023 · PreprintImmunology