Cancer BiologybioRxivPreprint
Single-cell transcriptome analysis reveals TOX as a promoting factor for T-cell exhaustion and a predictor for anti-PD1 responses in human cancer
K. Kim, S. Park, S. Y. Park…·I. Lee
The paper identifies TOX as a factor promoting T-cell exhaustion and predicts its role in anti-PD1 therapy outcomes using single-cell transcriptome data from cancer patients.