Single-Cell Transcriptomics Identifies Dysregulated Metabolic Programs of Aging Alveolar Progenitor Cells in Lung Fibrosis
J. Liang, G. Huang, X. Liu, F. Taghavifar, N. Liu, C. Yao, N. Deng, Y. Wangy, A. Burman, T. Xie, S. C. Rowan, P. Chen, C. M. Hogaboam, B. Stripp, S. S. Weigt, , D. Jiang
This study identifies metabolic defects in alveolar progenitor cells during aging and lung injury that impair their renewal capacity.
bioRxiv · Jul 30, 2020Cell Biology