Y. Wolf

{-}{-}{-}{-}{-}Polyglutamine-related aggregates serve as a potent antigen source for cross presentation by dendritic cells

The paper shows that polyglutamine-related aggregates from apoptotic cells are efficiently processed by dendritic cells for cross-presentation, ensuring antigenic overlap necessary for T cell immunity.

Diverse functions of closely homologous actin isoforms are defined by their nucleotide, rather than their amino acid sequence.

The paper shows that the functional distinction between β- and γ-actin is determined by their gene sequence, not their protein sequence, through genome editing in mice.