Pyroptotic cell-derived factors promote osteoclast differentiation
Yongjia Li, Chun Wang, 许灿新…·许灿新
This study shows that NLRP3CA-induced pyroptosis releases soluble proteins that promote osteoclast differentiation independently of IL-1β.
Author
Washington University in St. Louis
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
4 papers
Recent·Most cited
Yongjia Li, Chun Wang, 许灿新…·许灿新
This study shows that NLRP3CA-induced pyroptosis releases soluble proteins that promote osteoclast differentiation independently of IL-1β.
Wei Zou, Chun Wang, Yongjia Li…·Gabriel Mbalaviele
The paper shows that LPS-induced pyroptosis in bone marrow promotes periosteal bone formation by releasing factors that stimulate osteogenic differentiation of skeletal stem cells.
Saumya Bhagat, Khushpreet Kaur, Luke D O'Connor…·Gabriel Mbalaviele
This study shows S. aureus inhibits NLRP3 inflammasome activation in macrophages during early infection but not late infection, reducing bacterial load and pyroptosis.
Khushpreet Kaur, Yael Alippe, Chun Wang…·Gabriel Mbalaviele
The paper shows Tmem178 suppresses NLRP3 inflammasome activation in osteoclasts by limiting calcium release, preventing excessive bone resorption.