Khushpreet Kaur

This study shows that NLRP3CA-induced pyroptosis releases soluble proteins that promote osteoclast differentiation independently of IL-1β.

This study shows S. aureus inhibits NLRP3 inflammasome activation in macrophages during early infection but not late infection, reducing bacterial load and pyroptosis.

The paper shows Tmem178 suppresses NLRP3 inflammasome activation in osteoclasts by limiting calcium release, preventing excessive bone resorption.

This study identifies gene expression changes and pathways involved in osteoarthritis progression using synovial fluid transcriptomes from different OA grades.

This study shows doxorubicin causes bone loss via inflammasome activation, leading to pyroptosis and NETosis, and identifies AIM2 and NLRP3 as key mediators.