Integrin β3, a RACK1 interacting protein, is required for porcine reproductive and respiratory syndrome virus infection and NF-κB activation in Marc-145 cells
C. Yang, R. Lan, X. Wang, Zhao, X. Li, J. Bi, J. Wang, G. Yang, Y. Lin, J. Liu, G. Yin
This study identifies integrin β3 as a RACK1-interacting protein essential for PRRSV infection and NF-κB activation in Marc-145 cells, revealing a positive feedback loop involving NF-κB and ITGB3/RACK1.
bioRxiv · Jan 27, 2020Microbiology