R. Lan

A dissection of the genomic antimicrobial resistance epidemiology of Salmonella Typhimurium

The paper analyzes antimicrobial resistance in Salmonella Typhimurium using genomic data to identify resistant strains and their geographic and host associations.

Characterising Staphylococcus aureus genomic epidemiology with Multilevel Genome Typing.

This study develops a multilevel genome typing (MGT) scheme for Staphylococcus aureus to characterize genomic epidemiology at various scales using 50,481 genomes.

Proteomic comparison of epidemic Australian Bordetella pertussis biofilm cells

This study compares proteomic differences between two clusters of Bordetella pertussis strains in biofilm conditions, identifying strain-specific protein expression variations linked to cluster dominance.

Genomic epidemiology and multilevel genome typing of Bordetella pertussis

This paper introduces a multilevel genome typing system for Bordetella pertussis to improve surveillance and understanding of circulating strains and their public health risks.

SaLTy: a novel Staphylococcus aureus Lineage Typer

SaLTy is a new lineage typing method for Staphylococcus aureus that divides isolates into 61 phylogenetic lineages with high accuracy, improving on existing clonal complex classifications.

Integrating proteomic data with metabolic modelling provides insight into key pathways of Bordetella pertussis biofilms

This study integrates proteomic data with metabolic modeling to identify key metabolic pathway differences between biofilm and planktonic Bordetella pertussis cells.

Genomic dissection of the microevolution of Australian epidemic Bordetella pertussis

This study analyzes the genomic and phylogeographic dynamics of B. pertussis in Australia, revealing lineage expansion, selective sweeps, and spatial spread patterns linked to vaccination and transmission.

Transferrin receptor 1-mediated iron uptake regulates bone mass in mice via osteoclast mitochondria and cytoskeleton

This study shows that TFR1-mediated iron uptake in osteoclasts affects mitochondrial function and cytoskeleton, leading to increased bone mass in female mice.

Cluster-specific gene markers enhance Shigella and Enteroinvasive Escherichia coli in silico serotyping

This study identifies cluster-specific gene markers for Shigella and EIEC strains and develops a tool, ShigEiFinder, to accurately differentiate and serotype them with high accuracy.

Integrin β3, a RACK1 interacting protein, is required for porcine reproductive and respiratory syndrome virus infection and NF-κB activation in Marc-145 cells

This study identifies integrin β3 as a RACK1-interacting protein essential for PRRSV infection and NF-κB activation in Marc-145 cells, revealing a positive feedback loop involving NF-κB and ITGB3/RACK1.

Beyond a ribosomal RNA methyltransferase, the wider role of MraW in DNA methylation, motility and colonization in Escherichia coli O157:H7

This paper identifies MraW as a DNA methylase in E. coli O157:H7, showing its role in motility, colonization, and virulence through genome-wide methylation and regulation of flagellar genes.