Author

Olaf Merkel

Medical University of ViennaORCID 0000-0001-5089-344XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

Lukas KenneriD· 3 shared Michaela SchledereriD· 3 shared Boris TichýiD· 2 shared Heidi Anne NeubaueriD· 2 shared Richard MoriggliD· 2 shared Sandra HögleriD· 2 shared Torben RedmeriD· 2 shared Vojtěch BystrýiD· 2 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersCancer Biology

Lukas KennerORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintMar 30, 2026

Single-Cell Profiling Reveals Developmental Trajectories and identifies SYK and TIM3 as Targets in some T Cell Lymphomas

Ruoyan Li, Jamie D. Matthews, Emily R. James…·Suzanne Dawn Turner

This study uses single-cell transcriptomics to analyze T cell lymphomas, identifies developmental origins, and discovers SYK and TIM3 as potential therapeutic targets.

DOI 10.64898/2026.03.27.714741

humanscRNA-seq

𝕏 PostBluesky

Cancer BiologyMolecular CancerPeer-reviewedOct 14, 2025

Thyroid Hormone Receptor Beta Signaling is a Targetable Driver of Prostate Cancer Growth

Aleksandra Fesiuk, Daniel Pölöske, Elvin D. de Araujo…·Lukas Kenner

This study identifies TRβ as a driver of prostate cancer growth and shows that NH-3 inhibits PCa cell proliferation and tumor growth, particularly in castration-resistant models.

DOI 10.1186/s12943-025-02451-2

humanbulk RNA-seq

𝕏 PostBluesky

Cancer BiologyMolecular CancerPeer-reviewedMay 29, 2024

JUN mediates senescence and immune cell recruitment to prevent prostate cancer progression

Torben Redmer, Martin Raigel, Christina Sternberg…·Lukas Kenner

This study shows JUN suppresses prostate cancer progression by inducing senescence and immune cell recruitment, with JUN depletion accelerating tumor growth.

39 citationstop 3%

mousebulk RNA-seq

𝕏 PostBluesky