Vojtěch Bystrý

This study shows nanoplastics induce DNA mutations in Salmonella by disrupting DNA structure and altering mutational patterns through surface chemistry and DNA topology.

This study shows that paclitaxel resistance in triple-negative breast cancer is linked to DNA methylation changes, which can be partially reversed by decitabine to enhance chemosensitivity.

This study identifies TRβ as a driver of prostate cancer growth and shows that NH-3 inhibits PCa cell proliferation and tumor growth, particularly in castration-resistant models.

This study investigates the effects of Adar in Drosophila melanogaster, showing that overexpression of certain Adar isoforms leads to larval lethality and aberrant immune responses, with partial rescue through epigenetic modulation.

The paper identifies a Wnt-induced phospho-switch in DVL3 that regulates its interaction with Frizzled receptors and Wnt/β-catenin signaling through conformational changes.

This study shows that activating GP130 in prostate epithelial cells suppresses tumor growth through senescence and immune activation, suggesting a new therapeutic approach.

This study shows JUN suppresses prostate cancer progression by inducing senescence and immune cell recruitment, with JUN depletion accelerating tumor growth.

GLASS standardizes variant assessment from Sanger sequencing data, providing consistent output aligned with HGVS nomenclature.