Marie Tosolini

This study shows that sustained antigenic engagement leads to multidimensional remodeling and functional diversification of CTLs, maintaining cytotoxic activity while creating functionally distinct states.

The paper identifies immature and mature subsets of IFNγ-producing γδ T cells, showing IL-27 supports cytotoxic function in mature cells but not immature ones.

This study shows that meat-enriched diets and inflammation promote pancreatic cell plasticity via PI3Kα, which limits tissue regeneration and increases cancer risk.

The paper introduces an open-source software for analyzing spatial transcriptomics data, demonstrated on human and murine tissue datasets.

The paper introduces a software tool for analyzing and visualizing multimodal single-cell RNA-seq datasets, demonstrating its use on a CITE-seq dataset of PBMCs.

The paper introduces a tool for high-throughput scoring and visualization of gene set-based signatures across scRNA-seq datasets using t-SNE.