Annalise Bond

The paper shows that inhibitory Fc{gamma}RIIB limits macrophage signaling duration, while activating Fc receptors control sensitivity, using chimeric receptors and in silico modeling.

This study identifies an IL-10/ACOD1 axis that reprograms lipid metabolism in trained macrophages to promote resolution of inflammation.

This study shows CD47 inhibits Rac-mediated phagocytosis by preventing Vav1 phosphorylation, shifting the mechanism from Rac-based reaching to Rho-based sinking.

This study shows that prior Fc receptor activation primes macrophages to be more sensitive to IgG, enhancing phagocytosis through short- and long-term mechanisms.

The paper evaluates CSF1R inhibitors in tauopathy mice, finding sex-specific functional outcomes and suggesting sex-dependent effects on neuroprotection.