Author

Ayaka Sugiura

Vanderbilt University Medical CenterORCID 0000-0001-5326-5019Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Ayaka Sugiura1 paper · Wayne State University

Biology Disciplines

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Assay:bulk RNA-seq· 2 Approach:genetic perturbation / CRISPR· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

Andrew R. PattersoniD· 2 shared Channing ChiiD· 2 shared Darren R. HeintzmaniD· 2 shared Jeffrey C. RathmelliD· 2 shared A. R. ZhelonkiniD· 1 shared Allison E. SewelliD· 1 shared Allison K Blount· 1 shared Andrew P PahnkeiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersImmunology

Andrew R. PattersonORCID

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2 papers

Recent·Most cited

ImmunologyThe Journal of ImmunologyPeer-reviewedApr 9, 2025

Mitochondrial Fatty Acid Synthesis and Mecr Regulate CD4+ T Cell Function and Oxidative Metabolism

KayLee K. Steiner, Arissa Young, Andrew R. Patterson…·Jeffrey C. Rathmell

This study shows that Mecr, a mitochondrial fatty acid synthesis gene, is critical for CD4+ T cell metabolism, function, and survival, with implications for inflammatory diseases and mitochondrial disorders.

19 citationstop 2%

mousebulk RNA-seq

𝕏 PostBluesky

ImmunologybioRxivPreprintSep 13, 2023

Tissue-Specific Dependence of Th1 Cells on the Amino Acid Transporter SLC38A1 in Inflammation

Ayaka Sugiura, Katherine L. Beier, Channing Chi…·Jeffrey C. Rathmell

This study identifies tissue- and subset-specific roles of SLC38A1 in Th1 cell function during inflammation, showing its importance in EAE and IBD but not lung inflammation.

DOI 10.1101/2023.09.13.557496

mousebulk RNA-seq

𝕏 PostBluesky