Author

Maria A. Christophorou

Babraham InstituteORCID 0000-0001-5455-7283Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Biochemistry· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:database / resource· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:statistical model· 1

Frequent Co-Authors

Alexandra K.L.F.S. RebakiD· 1 shared Caroline LennartssoniD· 1 shared Charles ArnaliD· 1 shared Christine S. Young· 1 shared Christopher MapperleyiD· 1 shared Claus Henrik NielseniD· 1 shared Daniel MooreiD· 1 shared David Oxley· 1 shared

Activity by Year

2021-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 8 mutual co-author links

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1 shared paperMolecular Biology

Alexandra K.L.F.S. RebakORCID

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4 papers

Recent·Most cited

Molecular BiologybioRxivPreprintJan 30, 2025

The KRAB-Zinc Finger protein ZKSCAN3 represses enhancers via embedded retrotransposons

Daniel Moore, Eugenia Wong, Charles Arnal…·Maria A. Christophorou

This study shows ZKSCAN3 represses enhancers by targeting retrotransposons without forming heterochromatin, linking it to neurodevelopmental processes and schizophrenia.

3 citations

mouseexperimental assay

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BiochemistryNature CommunicationsPeer-reviewedNov 11, 2024

A cyclic peptide toolkit reveals mechanistic principles of peptidylarginine deiminase IV (PADI4) regulation

M. Teresa Bertran, Robert Walmsley, T. F. M. Cummings…·Louise J. Walport

The paper develops cyclic peptide modulators of PADI4 and reveals their mechanism of action and cellular activity.

29 citationstop 4%

humanproteomics

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Molecular BiologyNature Structural & Molecular BiologyPeer-reviewedFeb 6, 2024

A quantitative and site-specific atlas of the in vivo citrullinome reveals widespread existence of citrullination

Alexandra K.L.F.S. Rebak, Ivo Alexander Hendriks, Jonas Damgaard Elsborg…·Michael Lund Nielsen

The paper identifies 14,056 citrullination sites across 4,008 proteins using mass spectrometry, revealing widespread citrullination and its functional roles in histone marks and autoantigens.

45 citationstop 2%

humanproteomics

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Developmental BiologybioRxivPreprintApr 13, 2021

Peptidylarginine deiminase IV (PADI4) is not essential for cell-autonomous HSC maintenance and normal haematopoiesis

Christine S. Young, John R. Russell, Hannah Lawson…·Maria A. Christophorou

This study shows that PADI4 is not required for HSC maintenance, differentiation, or haematopoietic regeneration in mice.

2 citations

mouseexperimental assay

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