Sebla B. Kutluay

This study identifies TMEM106B as an alternative receptor for SARS-CoV-2 S-E484D variant entry, independent of ACE2, in airway-derived cell models.

The paper shows that HIV-1 integrase C-terminal domain mutations affect sensitivity to ALLINIs by altering gRNA binding, despite being distant from the drug binding site.

This study identifies APOBEC3G splicing defects in nonhuman primates that lead to different viral mutation profiles compared to humans.

This study shows that the adenosine-rich content of the HIV-1 genome is critical for efficient packaging, as demonstrated by Gag-SRSF5 chimera experiments.

This study identifies tonic activation of the cGAS-STING and IFN pathways in ACE2-positive airway cells as a factor limiting SARS-CoV-2 replication.

This study shows that thermodynamic coupling between tandem RRM domains of hnRNP A1 is essential for its allosteric RNA binding functions and stability under pressure.

The paper identifies RNA-protein interactomes of SARS-CoV-2 genomic and subgenomic RNAs, revealing new host factors involved in viral replication and antiviral defense.