Author
Washington University in St. LouisORCID 0000-0002-7571-4222Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Ming Xia, Qibo Wang, Maritza Puray-Chávez…·Sebla B. Kutluay
This study identifies TMEM106B as an alternative receptor for SARS-CoV-2 S-E484D variant entry, independent of ACE2, in airway-derived cell models.
Julius Chembo, Brittany M. Bowman, Kyle M. LaPak…·Michael B. Major
This paper identifies Pyrimethamine and its derivative WCDD115 as potent inhibitors of NRF2 by targeting DHFR and one-carbon metabolism, with WCDD115 showing 22-fold greater efficacy.
Maritza Puray‐Chavez, Jenna E. Eschbach, Ming Xia…·Sebla B. Kutluay
This study identifies tonic activation of the cGAS-STING and IFN pathways in ACE2-positive airway cells as a factor limiting SARS-CoV-2 replication.