Maider Astorkia

This study uses single-nucleus transcriptomics to show that perinatal SERT expression in CA3 pyramidal neurons affects gene expression in specific brain regions, with implications for social and spatial circuit development and autism-related genes.

This study shows that TCF1 expression drops before CD8 T cells divide, and this drop predicts their long-term fate as effectors or memory cells.

This study shows that total body irradiation before CAR T cell infusion enhances their effectiveness against large B-cell lymphoma by improving cytotoxicity and survival outcomes.

This study shows that FTSJ1-mediated tRNASec methylation enhances oxidative stress resistance and metastatic colonization in melanoma.

This study uses single-cell RNA-seq in cerebral organoids to analyze CHD8 heterozygous mutations, identifying altered gene expression, cell composition, and cell-cell communication linked to autism risk.

This study uses single cell RNA-seq data to analyze cell-cell communication differences in autistic brains compared to controls, identifying altered signaling pathways involving neurons and glia.