Mads Gyrd‐Hansen

The paper identifies insulin receptor ubiquitination as a regulator of collagen secretion in human skin through comparative ubiquitinomics of healthy and CYLD syndrome skin.

This paper develops a single-domain antibody specific for M1-linked ubiquitin chains, enabling their detection and analysis across multiple applications.

This study shows that OTULIN's interaction with LUBAC limits its activity, preventing TNF-driven inflammation and immunopathology.

This study shows LUBAC activates AMPK and OTULIN restricts it, affecting metabolic responses to energy stress in cells, mice, and flies.