Corey G. K. Flynn

This study shows that mTORC1 regulates myofibrillogenesis and radial myofibril growth in response to mechanical loading in mice.

This study identifies myofibril loss as the primary cause of muscle fiber atrophy in aging and disuse, using macroscopic to ultrastructural analyses in humans and mice.

This study shows mechanical loading induces muscle fiber growth through two mechanisms: mTORC1-dependent radial growth and mTORC1-independent longitudinal sarcomere addition.

This study identifies TRIM28's role in satellite cell-mediated myogenesis by regulating myomixer expression and fusion pore formation, independent of phosphorylation or proliferation/differentiation.

This study shows that mTORC1 inhibition accelerates the metabolic switch from glycolysis to fatty acid oxidation in neonatal heart injury, impairing regeneration.

The paper shows Hoxa11-expressing interstitial cells contribute to adult skeletal muscle fibers independently of satellite cells.

The paper creates an atlas of injured sciatic nerve cells and identifies immune microenvironments and communication networks in mouse nerve regeneration.

This study shows that shRNAs cause microRNA dysregulation and global transcriptomic changes in neurons, independent of their target.