Author

Jessy S. Deshane

University of Alabama at BirminghamORCID 0000-0002-6761-5662Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Kayla F. GoliwasiD· 3 shared Mohammad AthariD· 3 shared Kenneth P. HoughiD· 2 shared A Hassan D I Pritchard· 1 shared Aakash P. DesaiiD· 1 shared Balu K. ChackoiD· 1 shared Benjamin WeiiD· 1 shared Bharat MishraiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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3 shared papersImmunology

Kayla F. GoliwasORCID

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3 papers

Recent·Most cited

ImmunologyNature CommunicationsPeer-reviewedMay 26, 2026

Small Extracellular Vesicle Signaling and Mitochondrial Transfer Reprograms T Helper Cell Function in Human Asthma

Kenneth P. Hough, Jennifer L. Trevor, Shaheer Ahmad…·Jessy S. Deshane

This study shows that mitochondrial-containing sEVs from MDRCs activate and polarize Th17 and Th2 cells in asthma, contributing to airway inflammation.

8 citations

humanexperimental assay

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Cancer BiologybioRxivPreprintMay 19, 2025

Patient-Derived Three-Dimensional Lung Tumor Models to Evaluate Response to Immunotherapy

Kayla F. Goliwas, Kenneth P. Hough, Sruti Sivan…·Jessy S. Deshane

The paper develops a 3D lung tumor model to evaluate immunotherapy response and identifies biomarkers for predicting immune checkpoint inhibitor efficacy in NSCLC.

DOI 10.1101/2025.05.19.654890

humanspatial transcriptomics

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ImmunologybioRxivPreprintOct 31, 2023

NK and NKT cells in the pathogenesis of Hidradenitis suppurativa: Novel therapeutic strategy through targeting of CD2

Mahendra Pratap Kashyap, Bharat Mishra, R. Sinha…·Chander Raman

This study identifies expanded NKT and NK cells with elevated CD2 in HS lesions and shows CD2 blockade reduces inflammation and fibrosis.

2 citations

humanscRNA-seq

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