Viviane Souza de Campos

This study investigates how reduced substrate stiffness affects corneal endothelial cell health, finding increased FAK activity and EndMT, but no improvement in disease progression with FAK inhibition.

This study shows proteasomal dysfunction causes ER stress, endo-mesenchymal transition, oxidative stress, and apoptosis in mice, leading to FECD-like features.

This paper develops a mouse model that recapitulates all major features of Fuchs Endothelial Corneal Dystrophy (FECD) through combined genetic and dietary manipulations.