Dillon E Sloan

The paper investigates how CCDC32 interacts with AP-2 to regulate its assembly, revealing that CCDC32 inhibits assembly and requires membrane binding for complex formation.

The paper shows that the ATPase function of DPY-27 in C. elegans is essential for dosage compensation by enabling DNA binding, X-chromosome condensation, and H4K20me1 enrichment.

The paper investigates how securin degradation by APC/C controls separase localization and function during meiosis I, showing its role in chromosome segregation and exocytosis.

This study identifies novel separase regulators in C. elegans through an ENU mutagenesis screen, revealing mutations in pph-5 and hsp-90 that suppress a separase mutant phenotype.