Sadhna Phanse

The paper maps protein interaction network remodeling in a mouse tauopathy model using multi-omics and machine learning, identifying key complexes involved in early disease phenotypes.

This study generates CHCHD2 T61I mutant mice to model Parkinson's disease, finding mitochondrial dysfunction and metabolic shifts towards glycolysis.

This study shows GlpG protease is essential for type 1 pili assembly in E. coli, affecting biofilm formation and bacterial fitness.

This study identifies YibN as a functional interactor of YidC, showing it enhances membrane protein insertion and lipid production in bacteria.

The paper maps EMT transitions through multi-omic profiling, identifies key regulatory factors, and reveals discordance between molecular layers in human mammary epithelial cells.

This study uses a chemical-genetic approach to analyze resistance determinants of E. coli to 15 AMPs, revealing cross-resistance and collateral sensitivity patterns.