Hae‐Ji Kang

This study evaluates late-onset antiviral treatment in immunocompromised mice with persistent SARS-CoV-2 infection, finding that 4-FlU significantly reduces virus load, while paxlovid causes viral rebound.

This study identifies mutations conferring resistance to 4-fluorouridine in influenza viruses and shows that resistant variants are attenuated in vivo and can be overcome by higher drug doses.

The paper shows that segmented filamentous bacteria reprogram alveolar macrophages to enhance non-inflammatory defense against respiratory viruses.