Author
Memorial Sloan Kettering Cancer CenterORCID 0000-0001-6452-8152Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Simon A. Grassmann, Endi K. Santosa, Hyunu Kim…·Joseph Chai-Yuen Sun
This study shows that interleukin-12 signaling integrates with antigen receptor signals in a context-dependent manner to determine the epigenetic and functional fate of cytotoxic lymphocytes.
Simon A. Grassmann, Hyunu Kim, Christin Friedrich…·Joseph Chai-Yuen Sun
This study shows STAT3 acts as an inflammation-dependent transcriptional switch in NK cells, regulating differentiation through MYB and BLIMP-1 under different inflammatory conditions.
Yahui Guo, Mariano A. Aufiero, Kathleen A M Mills…·Tobias M. Hohl
The paper identifies an IFN-STAT1-CYBB axis that mediates protective crosstalk between plasmacytoid dendritic cells and neutrophils during Aspergillus fumigatus infection.
Youngjun Kim, Francesca Manara, Simon A. Grassmann…·Jayanta Chaudhuri
This study reveals that IL-21 regulates B cell fate through context-dependent effects on apoptosis and proliferation, using a conditional knock-out model and ex vivo cultures.