Galia T. Debelouchina

This study investigates how electrostatic interactions influence HP1α phase separation and its interactions with binding partners, showing that these interactions modulate HP1's properties and functions.

This paper introduces a degron decoy system that uses pathological seeding to clear multimeric α-synuclein by co-aggregating with oligomers and enabling degradation via a small molecule trigger.

This paper characterizes the structure and dynamics of HSPB1 oligomers using biophysical and computational methods, revealing conformational heterogeneity and domain-specific interactions.

This study shows phosphorylation disrupts tau's ability to undergo phase separation and interact with chromatin, potentially contributing to nuclear dysfunction in Alzheimer's disease.