Patrick S. Creisher

This study develops a mouse model of echovirus infection and identifies humoral correlates of protection against the virus.

This study uses single-nucleus RNA sequencing and organoids to identify unique placental cell types and immune adaptations in Jamaican fruit bats, revealing species-specific gene programs and attenuated antiviral responses in trophoblasts.

This study identifies sex differences in long COVID sequelae in mice, showing that X-linked genes like Xist and Tlr7 contribute to persistent inflammation and cognitive impairments in females.

This study infects pregnant mice with Plasmodium berghei at different gestational stages to investigate how placental malaria affects perinatal outcomes and identifies immune and hormonal changes associated with adverse effects.

This study shows estradiol enhances germinal center responses and antibody production in female mice after influenza vaccination, leading to better protection against viral challenge.

This study shows that influenza A virus suppresses progesterone in pregnant mice, leading to adverse maternal and fetal outcomes, which can be mitigated by progestin treatment.