Author

Yahui Yan

University of CambridgeORCID 0000-0001-6934-9874Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Biochemistry· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:human· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Approach:mechanistic / dynamical model· 1 Assay:proteomics· 1

Frequent Co-Authors

David RoniD· 2 shared Alisa F. ZyryanovaiD· 1 shared Amirhossein MafiiD· 1 shared Carmela SidrauskiiD· 1 shared Ginto GeorgeiD· 1 shared Heather P. HardingiD· 1 shared Jakub MilczarekiD· 1 shared Joanne TungiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiochemistry

David RonORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

BiochemistrybioRxivPreprintApr 14, 2025

A structural basis for chaperone repression of stress signalling from the endoplasmic reticulum

Lisa Neidhardt, Joanne Tung, Miriam Kuchersky…·Yahui Yan

This study identifies how AGR2 chaperone forms a dimer to repress IRE1β dimerization and suppress the UPR by blocking its activating conformation.

DOI 10.1101/2025.04.14.648677

humanstructural biology

𝕏 PostBluesky

BiochemistryProceedings of the National Academy of SciencesPeer-reviewedMar 28, 2024

Substrate recruitment via eIF2γ enhances catalytic efficiency of a holophosphatase that terminates the Integrated Stress Response

Yahui Yan, Maithili Shetty, Heather P. Harding…·David Ron

The paper identifies a mechanism by which eIF2γ binding to PPP1R15A enhances catalytic efficiency of the holophosphatase that terminates the integrated stress response.

7 citations

humanproteomics

𝕏 PostBluesky