Author

Amirhossein Mafi

Calico Life SciencesORCID 0000-0002-8366-6785Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:mechanistic / dynamical model· 1 Assay:protein structure· 1 Assay:proteomics· 1

Frequent Co-Authors

Qi HaoiD· 2 shared Aaron H. NileiD· 1 shared Alisa F. ZyryanovaiD· 1 shared Andrei LoasiD· 1 shared Anthony J. QuartararoiD· 1 shared Bradley L. PenteluteiD· 1 shared Carmela SidrauskiiD· 1 shared Dan EatoniD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiochemistry

Qi HaoORCID

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2 papers

Recent·Most cited

BiochemistryProceedings of the National Academy of SciencesPeer-reviewedMar 28, 2024

Substrate recruitment via eIF2γ enhances catalytic efficiency of a holophosphatase that terminates the Integrated Stress Response

Yahui Yan, Maithili Shetty, Heather P. Harding…·David Ron

The paper identifies a mechanism by which eIF2γ binding to PPP1R15A enhances catalytic efficiency of the holophosphatase that terminates the integrated stress response.

7 citations

humanproteomics

𝕏 PostBluesky

Molecular BiologyChemical SciencePeer-reviewedJan 1, 2023

Discovery of reactive peptide inhibitors of human papillomavirus oncoprotein E6

Xiyun Ye, Peiyuan Zhang, Jason Tao…·Bradley L. Pentelute

The paper designs a covalent peptide inhibitor, reactide, targeting the HPV16 E6-E6AP interaction to prevent p53 degradation.

22 citations

humanprotein structure

𝕏 PostBluesky