Design of intrinsically disordered region binding proteins
Kejia Wu, Hanlun Jiang, Derrick R. Hicks…·David A. Baker
The paper designs proteins that bind intrinsically disordered regions with high affinity and specificity across diverse targets.
Author
University of WashingtonORCID 0000-0001-7000-5219Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Kejia Wu, Hanlun Jiang, Derrick R. Hicks…·David A. Baker
The paper designs proteins that bind intrinsically disordered regions with high affinity and specificity across diverse targets.
Hui Chin Peng, Ying‐Wai Lam, Kwok‐Fai Lau…·Chris W. Lee
This study quantifies the functional impact of GALC missense variants in Krabbe disease, showing strong correlations between residual enzyme activity, clinical severity, and psychosine levels.
Vi Pham, Lívia Sertori Finoti, Margaret M. Cassidy…·Rebecca C. Ahrens‐Nicklas
This paper creates an iPSC model of Multiple Sulfatase Deficiency, showing that neurons become more vulnerable to SUMF1 loss during differentiation.