Abigail A. Harrington

This study identifies gain-of-resistance mutations in FKS2 causing heteroresistance in Candida glabrata through heterogeneous gene expression, and shows regulators like calcineurin and IRA1 influence this phenomenon.

This study identifies calcineurin signaling as a regulator of echinocandin tolerance and persistence in Candida glabrata and Candida albicans, suggesting potential therapeutic strategies.

This study uses Tn-seq to analyze genetic and epigenetic variation in Candida glabrata strains, revealing structural differences, resistance mechanisms, and subtelomeric chromatin accessibility.

This study identifies calcineurin-dependent genes and pathways critical for fitness in Candida glabrata under various stress conditions, highlighting roles in cell wall biosynthesis and vesicular trafficking.