Andrew N. Gale

This study uses Tn-seq to analyze genetic and epigenetic variation in Candida glabrata strains, revealing structural differences, resistance mechanisms, and subtelomeric chromatin accessibility.

This study identifies calcineurin-dependent genes and pathways critical for fitness in Candida glabrata under various stress conditions, highlighting roles in cell wall biosynthesis and vesicular trafficking.

This study identifies new genes and mechanisms regulating fluconazole resistance in C. glabrata, showing Pdr1 senses cellular stress rather than directly responding to antifungals.

The paper presents a highly contiguous genome and transcriptome of Candida nivariensis, assembled using Oxford Nanopore and Illumina sequencing.

The paper identifies essential genes and fluconazole resistance genes in Candida glabrata using Hermes transposon insertion profiling and machine learning.

The paper compares transposon mutagenesis methods in yeast to infer gene essentiality, finding biases in insertion sites and recommending transposon choices for accurate essentiality prediction.