Sylvie Alonso

This paper identifies an IFNγ-CXCL9-CXCR3 axis linking T cell recruitment to skeletal muscle remodelling in human physical frailty, showing its association with fibrosis and potential therapeutic targets.

The paper shows a dengue virus mutant lacking N153 glycosylation is more susceptible to neutralizing antibodies, as evidenced by increased Fab occupancy and slower dissociation rates.

A nasal booster vaccine candidate induced cross-clade, durable, systemic and mucosal immunity in mRNA-vaccinated mice, offering superior protection against emerging sarbecoviruses.

This study shows that N153-linked glycans on dengue virus envelope protein help evade antibody-mediated clearance, with implications for immune evasion in related flaviviruses.

This study identifies a novel aglain derivative that effectively inhibits EV-A71 replication and shows broad antiviral activity against enteroviruses.

This study shows that de-glycosylation of N207 in DENV NS1 reduces viral fitness and enhances clearance by limiting PD-L1/PD-1 mediated T cell apoptosis.

This study maps the structural interactions of dengue and Zika viruses, identifying functional long-range interactions and their role in viral replication and attenuation.