Jan K. Marzinek

This study uses multiscale simulations to reveal how SDS disrupts MS2 bacteriophage capsid, showing pH-dependent effects and molecular mechanisms of surfactant-virus interaction.

This study uses multiscale modeling, lipidomics, and experiments to engineer stable and immunogenic dengue virus-like particles by modifying protein-lipid interactions.

The paper investigates how lipid A modifications in Yersinia species influence pathogenicity by altering TLR4 recognition and inflammation.

This study shows that N153-linked glycans on dengue virus envelope protein help evade antibody-mediated clearance, with implications for immune evasion in related flaviviruses.

This study presents the cryo-EM structure of immature dengue serotype 2 VLPs and uses MD simulations to reveal their maturation mechanism and lipid dependency.

This paper develops a coarse-grained model for glycosaminoglycans compatible with Martini forcefields, enabling simulation of their conformational and thermodynamic properties.

This study shows that de-glycosylation of N207 in DENV NS1 reduces viral fitness and enhances clearance by limiting PD-L1/PD-1 mediated T cell apoptosis.