Bastiaan J. Viergever

The paper identifies location-specific transcriptional differences in tumor-infiltrating Treg cells across CRC metastases and links these to poor patient prognosis.

This study shows that combining ATR inhibitors with mitomycin C significantly reduces viability of NMIBC organoids compared to chemotherapy or ATR inhibitors alone.

This study shows that pre-existing subclones in rectal cancer organoids determine radioresistance, with resistance linked to reduced chromosomal instability.