Fredrick Joseph Rosario

This study knocks down mTOR in trophoblasts of late pregnant mice, reducing placental nutrient transport and fetal growth.

The paper develops a robust segmentation and statistical analysis pipeline for neuronal primary cilia in brain tissue, showing significant group differences in a mouse model of maternal obesity.

This study shows claudin-4 promotes genomic instability tolerance in ovarian cancer by linking cell junctions to autophagy via SLC1A5/LAT1, and targeting it enhances PARPi efficacy.